Metabolic Pathway Engineering

Novacta Biosystems is a world leader in the pathway engineering of both primary and secondary metabolism in micro organisms - including species that are difficult to engineer, such as Actinomycetes, Thermophiles, Bacillus species and yeasts.

Since its inception Novacta has worked with blue chip pharmaceutical and biofuel companies interested to improve the sysnthesis of natural products, platform chemicals or biofuels.

Novacta differentiates itself from the competition by its ability to adopt both conventional genetics and metabolic pathway engineering. Our team has in-depth experience in:

- Molecular biology - cloning and sequencing of biosynthetic pathways, heterologous expression, up/down regulation of desired pathways, insertion/ mutation of new genes to manipulate the chemical product and the generation of libraries of analogues through genetic engineering

- Classical genetics, mutagenesis and strain improvement by mutation and selection

- Microbiology and fermentation expertise

- Enzyme production and purification

Why work with Novacta

  • Know how and team
  • Track record of sucessfully completing challenging projects
  • Capacity to work on various organisms and products
  • Successful manipulation of industrial organisms rather than model organisms
  • Combination of conventional genetics and molecular biology approaches
  • Speed
  • IPR belongs to the customer